UJI AMILUM BATANG KELAPA SAWIT (Elaeis guineensis Jacq.) SEBAGAI BAHAN PENGISI PADA TABLET KLORFENIRAMIN MALEAT (CTM) DENGAN METODE GRANULASI BASAH

Stepanus Rapael .

Abstract


The waste from palms trunk was consist of starch which expected can be used astablet filler material. This research was to test the palms trunk starch aschlorpheniramine maleat (CTM) tablet filler material and to test its physics. Tablet fillermaterial in comparation formulae was using the lactose (K1) and the test tablet formulaewas using the palms trunk starch (K2). The tablet was made by the wet granulationmethod. The physics tests result of both formula showed that the tablet had eligible resultin the uniformity of weight, friability, hardness, disintegration period, assay, contentuniformity, and tablets dissolution test. The analysis independent T test result by usingSPSS 17.0 showed that p<0,05 so the both formula was different, except for the contentuniformity and tablets dissolution test. The palms trunk starch can be used as CTMtablet filler material with the physics characteristic wasnt as good as the comparationformulae tablet.
Keywords : Palms Trunk Starch, Tablet, Filler Material and CTM.

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