Hubungan paparan asap rokok dengan hasil pemeriksaan inspeksi visual asam asetat (IVA) pada wanita usia subur di Puskesmas Tanjung Sekayam

Fikri Yuda Pratama, Eka Ardiani Putri, Widi Raharjo

Abstract


Latar belakang: Tembakau yang dijadikan rokok selain berdampak pada perokok juga berdampak bagi orang yang tidak merokok. Karsinogen dalam asap rokok dapat menyebabkan kanker salah satunya kanker serviks. Kanker serviks merupakan kanker keempat yang paling sering terjadi pada wanita di dunia. Deteksi dini kanker serviks dapat dilakukan dengan metode inspeksi visual asam asetat (IVA). Tujuan penelitian ini untuk mengetahui hubungan paparan asap rokok dengan hasil IVA pada wanita usia subur. Metode: Desain penelitian ini merupakan analitik observasional dengan pendekatan cross-sectional. Subjek penelitian diambil dari wanita yang melakukan pemeriksaan IVA di wilayah kerja Puskesmas Tanjung Sekayam dengan cara consecutive sampling sebanyak 40 wanita usia 30 – 50 tahun. Analisis bivariat dilakukan dengan uji fisher exact. Hasil: 30 orang (75%) terpapar asap rokok dan 10 orang (25 %) tidak terpapar asap rokok, 39 orang (97,5%) memperoleh hasil IVA negatif dan 1 orang (2,5%) memperoleh hasil IVA positif. Analisis bivariat paparan asap rokok dan hasil IVA diperoleh nilai p=1,000, intensitas paparan asap rokok per hari dan hasil IVA wanita terpapar asap rokok diperoleh nilai p=0,433, durasi paparan asap rokok per hari dan hasil IVA wanita terpapar asap rokok diperoleh nilai p=0,367. Kesimpulan: Tidak terdapat hubungan paparan asap rokok dengan hasil IVA, tidak terdapat hubungan intensitas dan durasi paparan asap rokok per hari dengan hasil IVA wanita terpapar asap rokok.

Keywords


hasil pemeriksaan IVA;kanker serviks;paparan asap rokok

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References


World Health Organization. Tobacco [Internet]. Who.int. 2018 [cited 2019 Feb 9]. Available from: https://www.who.int/news-room/fact-sheets/detail/tobacco

World Health Organization. Prevalence of tobacco smoking [Internet]. Who.int. 2016 [cited 2019 Feb 9]. Available from: http://www.who.int/gho/tobacco/use/en/

World Health Organization. Second-hand tobacco smoke [Internet]. Who.int. 2015 [cited 2019 May 8]. Available from: https://www.who.int/tobacco/research/secondhand_smoke/en/

American Cancer Society. Health Risks of Secondhand Smoke [Internet]. Cancer.org. 2015 [cited 2019 May 8]. Available from: https://www.cancer.org/cancer/cancer-causes/tobacco-and-cancer/secondhand-smoke.html

Asma S, Mackay J, Song SY, Zhao L, Morton J, Bettcher KMPD, et al. The GATS atlas: Global adult tobacco survey. Atlanta: CDC Foundation; 2015.

Badan Penelitian dan Pengembangan Kesehatan. Riset Kesehatan Dasar 2018. Kementerian Kesehatan RI; 2018.

U.S. Department of Health and Human Services. The Health Consequences of Smoking - 50 Years of progress: A Report of the Surgeon General [Internet]. Rockville: American Psychological Association; 2014 [cited 2019 Feb 10]. Available from: http://doi.apa.org/get-pe-doi.cfm?doi=10.1037/e510072014-001

Su B, Qin W, Xue F, Wei X, Guan Q, Jiang W, et al. The relation of passive smoking with cervical cancer: A systematic review and meta-analysis. Medicine (Baltimore). 2018;97(46):e13061.

Min K-J, Lee J-K, So KA, Kim MK. Association Between Passive Smoking and the Risk of Cervical Intraepithelial Neoplasia 1 in Korean Women. J Epidemiol. 2018;28(1):48–53.

Zeng X-T, Xiong P-A, Wang F, Li C-Y, Yao J, Guo Y. Passive Smoking and Cervical Cancer Risk: A Meta-analysis Based on 3,230 Cases and 2,982 Controls. Asian Pac J Cancer Prev. 2012;13:2688–91.

World Health Organization. Cervical cancer [Internet]. Who.int. 2019 [cited 2019 Feb 10]. Available from: http://www.who.int/cancer/prevention/diagnosis-screening/cervical-cancer/en/

International Agency for Research on Cancer. Indonesia - Global Cancer Observatory [Internet]. World Health Organization; 2019. Available from: http://gco.iarc.fr/today/data/factsheets/populations/360-indonesia-fact-sheets.pdf

Kementerian Kesehatan RI. Profil Kesehatan Indonesia Tahun 2017. Jakarta: Kementerian Kesehatan RI; 2018.

Kementerian Kesehatan RI. Penanggulangan Kanker Payudara dan Kanker Leher Rahim. Jakarta: Kementerian Kesehatan RI; 2015.

Kementerian Kesehatan RI. Data dan Informasi Profil Kesehatan Indonesia 2018. Jakarta: Kementerian Kesehatan RI; 2019.

Dinas Kesehatan Kabupaten Sanggau. Profil Kesehatan Kabupaten Sanggau 2018. Sanggau: Dinas Kesehatan Kabupaten Sanggau; 2019.

Nkfusai NC, Mubah TM, Yankam BM, Tambe TA, Cumber SN. Prevalence of precancerous cervical lesions in women attending Mezam Polyclinic Bamenda, Cameroon. Pan Afr Med J. 2019;32:174.

World Health Organization. Comprehensive Cervical Cancer Control : A guide to essential practice. 2nd ed. Geneva: World Health Organization; 2014.

Damiani G, Basso D, Acampora A, Bianchi CBNA, Silvestrini G, Frisicale EM, et al. The impact of level of education on adherence to breast and cervical cancer screening: Evidence from a systematic review and meta-analysis. Prev Med. 2015;81:281–9.

Mesalina R, Sulung N, Nurhayati. Sosio demografi perempuan pemanfaatan deteksi dini kanker serviks metode IVA di Bukittinggi. J Hum Care. 2019;4(2):64–75.

Ursia CC, Warsanto J, Isbadianti E. Visual inspection with acetic acid (VIA) positive result and passive smoker in Puskesmas Wonoayu Sidoarjo. Journal of Widya Medika Junior. 2020;2(2):86–94.

An L, Zhou X, Li W, Wang Y, Shi H, Xie T. Association between secondhand smoke exposure and abnormal cervical cytology: A one-to-one matched case-control study. Tob Induc Dis. 2018;16:56.

Chung MH, McKenzie KP, De Vuyst H, Richardson BA, Rana F, Pamnani R, et al. Comparing Papanicolau smear, visual inspection with acetic acid and human papillomavirus cervical cancer screening methods among HIV-positive women by immune status and antiretroviral therapy. AIDS Lond Engl. 2013;27(18):2909–19.

Feng R-M, Hu S-Y, Zhao F-H, Zhang R, Zhang X, Wallach AI, et al. Role of active and passive smoking in high-risk human papillomavirus infection and cervical intraepithelial neoplasia grade 2 or worse. J Gynecol Oncol. 2017;28(5):e47.

Du X, Li M, Zhou Y, Yang H, Isachenko V, Takagi T, et al. Evidence of Passive Smoking as a Risk Factor of High-Grade Squamous Intraepithelial Lesion: A Case-Control Study. Biol Pharm Bull. 2020;43(7):1061–6.

Ward KK, Berenson AB, Breitkopf CR. Passive smoke exposure and abnormal cervical cytology in a predominantly Hispanic population. Am J Obstet Gynecol. 2011;204(3):213.e1-213.e6.

Dewi IGAAN, Sawitri AAS, Adiputra N. Paparan asap rokok dan higiene diri merupakan faktor risiko lesi prakanker leher rahim di Kota Denpasar tahun 2012. Public Health Prev Med Arch. 2013;1(1):84–91.

Simen-Kapeu A, Kataja V, Yliskoski M, Syrjänen K, Dillner J, Koskela P, et al. Smoking impairs human papillomavirus (HPV) type 16 and 18 capsids antibody response following natural HPV infection. Scand J Infect Dis. 2008;40(9):745–51.

Kum-Nji P, Meloy L, Keyser-Marcus L. Tobacco smoke exposure as a risk factor for human papillomavirus infections in women 18-26 years old in the United States. PLOS ONE. 2019;14(10):e0223532.

Louie KS, Castellsague X, de Sanjose S, Herrero R, Meijer CJ, Shah K, et al. Smoking and passive smoking in cervical cancer risk: pooled analysis of couples from the IARC multicentric case-control studies. Cancer Epidemiol Biomark Prev. 2011;20(7):1379–90.

Ono A, Nakagawa M, Ikuta E, Watanabe Y, Koshiyama M. Relationship between Tobacco Smoking and Cervical Cancer. Women Health Open J. 2019;5(1):19–21.

Chen L, Wang H. Nicotine Promotes Human Papillomavirus (HPV)-Immortalized Cervical Epithelial Cells (H8) Proliferation by Activating RPS27a-Mdm2-P53 Pathway In Vitro. Toxicol Sci Off J Soc Toxicol. 2019;167(2):408–18.

Schabath MB, Villa LL, Lazcano-Ponce E, Salmerón J, Quiterio M, Giuliano AR. Smoking and Human Papillomavirus (HPV) Infection in the HPV in Men (HIM) Study. Cancer Epidemiol Biomark Prev. 2012;21(1):102–10.

Nielson CM, Harris RB, Dunne EF, Abrahamsen M, Papenfuss MR, Flores R, et al. Risk Factors for Anogenital Human Papillomavirus Infection in Men. J Infect Dis. 2007;196(8):1137–45.

Ingles DJ, Lin H-Y, Fulp WJ, Sudenga SL, Lu B, Schabath MB, et al. An analysis of HPV infection incidence and clearance by genotype and age in men: The HPV Infection in Men (HIM) Study. Papillomavirus Res. 2015 Oct 8;1:126–35.

Coker AL, Bond SM, Williams A, Gerasimova T, Pirisi L. Active and passive smoking, high-risk human papillomaviruses and cervical neoplasia. Cancer Detect Prev. 2002;26(2):121–8.

Seo S-S, Oh HY, Kim MK, Lee DO, Chung YK, Kim J-Y, et al. Combined Effect of Secondhand Smoking and Alcohol Drinking on Risk of Persistent Human Papillomavirus Infection. BioMed Res Int. 2019;2019:5829676.

Hwang LY, Ma Y, Benningfield SM, Clayton L, Hanson EN, Jay J, et al. Factors that influence the rate of epithelial maturation in the cervix of healthy young women. J Adolesc Health. 2009;44(2):103–10.

Miranda PM, Silva NNT, Pitol BCV, Silva IDCG, Lima-Filho JL, Carvalho RF, et al. Persistence or Clearance of Human Papillomavirus Infections in Women in Ouro Preto, Brazil. BioMed Res Int. 2013;2013:e578276.




DOI: http://dx.doi.org/10.26418/jc.v6i3.45317

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