FORMULASI SEDIAAN GEL ANTISEPTIK FRAKSI POLAR DAUN KESUM (Polygonum minus Huds)

Syari Wahyuni Ansiah .

Abstract


Antiseptic is usually use to against microorganism at the surface of body.
One of the plant that has antibacterial activity is kesum (Polygonum minus Huds).
The purpose of this experiment is to know which antiseptic gel containing polar
fraction of kesum leaves that show the best antiseptic power and physic and
chemical stability.This research included antibacterian activity test of polar
fraction, formulation gel of polar fraction, effectivity test of polar fraction gel and
stability test. Data that has been analyzed statistically by using One Way ANOVA
test. The test result showed  that  kesum leaves polar  fraction at concentration 5%,
10% dan 15% gave antibacterial activity and then they were formulated in
antiseptic gel product. The result showed that kesum leaves polar fraction gel had
antiseptic power. The three gels had similar stability in organoleptic test. Gel III
with 15% concentration of polar fraction underwent the least of viscosity
decreasing. Gel II with 10% concentration of polar fraction underwent the least of
thicking ability decreasing, pH, and spread ability increasing. 
Keyword : kesum leaves, gel, antiseptic, Escherichia coli

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